{"id":19795,"date":"2022-06-09T17:24:51","date_gmt":"2022-06-09T17:24:51","guid":{"rendered":"https:\/\/updates-www.mccdn.io\/vitals\/?p=19795"},"modified":"2024-04-02T16:30:54","modified_gmt":"2024-04-02T16:30:54","slug":"multicare-researchers-invention-improves-quality-of-life-for-survivors-of-stroke-and-other-medical-conditions","status":"publish","type":"post","link":"https:\/\/updates-www.mccdn.io\/vitals\/multicare-researchers-invention-improves-quality-of-life-for-survivors-of-stroke-and-other-medical-conditions\/","title":{"rendered":"MultiCare researcher\u2019s invention improves quality of life for survivors of stroke and other medical conditions","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p>Once every second \u2014 on average that\u2019s how often we take a step while walking. Many of us are concerned with the accumulation of those steps \u2014 striving for 10,000 a day, perhaps \u2014 rather than the mechanics of each one, but not David Embrey, PT, PhD.<\/p>\n<p>Embrey, a retired pediatric physical therapist at MultiCare and founder of the <a href=\"https:\/\/www.marybridge.org\/services\/rehabilitation-physical-therapy\/research-movement-lab\/\">Research and Movement Laboratory at Mary Bridge Good Samaritan Children\u2019s Therapy Unit<\/a>, had an epiphany back in 2004 that led to the development of the Gait MyoElectric Stimulator (GMES). This medical device is designed to help the millions of people with conditions that affect their ability to walk, for example, those who have suffered a stroke, live with cerebral palsy or have peripheral artery disease.<\/p>\n<p>The evolution of an idea into a product takes patience \u2014 18 years\u2019 worth and counting \u2014 but now Embrey is closer than ever to sharing his life-changing invention with the people who need it. He and MultiCare are collaborating with the <a href=\"https:\/\/ii4change.com\/innovation-lab\/\" target=\"_blank\" rel=\"noopener\">Innovation Institute<\/a> to make the GMES widely available to patients.<\/p>\n<h2><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-19799\" src=\"https:\/\/updates-www.mccdn.io\/vitals\/wp-content\/uploads\/sites\/15\/2022\/06\/DavidEmbrey-1024x576.jpg\" alt=\"Man smiling in garden\" width=\"1024\" height=\"576\" srcset=\"https:\/\/updates-www.mccdn.io\/vitals\/wp-content\/uploads\/sites\/15\/2022\/06\/DavidEmbrey-1024x576.jpg 1024w, https:\/\/updates-www.mccdn.io\/vitals\/wp-content\/uploads\/sites\/15\/2022\/06\/DavidEmbrey-300x169.jpg 300w, https:\/\/updates-www.mccdn.io\/vitals\/wp-content\/uploads\/sites\/15\/2022\/06\/DavidEmbrey-768x432.jpg 768w, https:\/\/updates-www.mccdn.io\/vitals\/wp-content\/uploads\/sites\/15\/2022\/06\/DavidEmbrey-1536x864.jpg 1536w, https:\/\/updates-www.mccdn.io\/vitals\/wp-content\/uploads\/sites\/15\/2022\/06\/DavidEmbrey-2048x1152.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/h2>\n<h2>The vision of a lifetime<\/h2>\n<p>The day inspiration came knocking, Embrey was sitting in front of his computer examining the electromyography results of children walking. Electromyography is a diagnostic test that shows how well muscles fire during a specific action.<\/p>\n<p>As he performed a tedious measuring task on his screen, Embrey began to think about an upcoming meeting with a colleague later that afternoon. For months, Embrey and his colleague had been trying to come up with a new research idea that could potentially benefit children with cerebral palsy. It was a mission that was personal for Embrey.<\/p>\n<p>\u201cMy brother has cerebral palsy,\u201d says Embrey. \u201cHe was the inspiration for my career as a pediatric physical therapist and it was his experience with mobility issues that drove my research interests as well.\u201d<\/p>\n<p>As Embrey sat in front of his computer that day \u2014 the impending meeting with his colleague and their lack of viable ideas looming large in his mind \u2014 he grew frustrated. He threw his hands in the air, looked up at the ceiling and said, \u201cI\u2019m supposed to see something, but I just don\u2019t. I\u2019m just not smart enough!\u201d<\/p>\n<p>But then his moment of despair transformed into one of insight.<\/p>\n<p>\u201cI looked back at my computer screen, and there the invention was in its entirety,\u201d Embrey says. \u201cI call it my divine vision.\u201d<\/p>\n<h2>Partnership, a prototype and the road to development<\/h2>\n<p>To help turn his vision into reality, Embrey collaborated with two partners: Jeff Stonestreet, a retired electrical engineer from Boeing; and Gad Alon, PT, PhD, associate professor emeritus at the University of Maryland.<\/p>\n<p>Together, the three of them created a prototype of the GMES, an electrical stimulation system that helps control muscle contraction and joint movement and improve stability while walking. Designed to be worn on the leg, undetectable beneath one\u2019s clothes, the GMES achieves its aim by delivering a slight electrical pulse to the shin and calf muscles.<\/p>\n<p>\u201cWhat\u2019s unique about the GMES is that it reads the body. It sends electrical impulses so that the correct muscles contract and relax at exactly the right time,\u201d says Embrey. \u201cSo, for example, if you\u2019re in a crosswalk and you see a car coming, you\u2019re likely to step faster. The GMES will read the body\u2019s intention and speed up or slow down the stepping process as necessary.\u201d<\/p>\n<p>The electrical impulse itself is mild. Embrey equates it to a light tingling or pulsating sensation that most people lose awareness of after they\u2019ve worn the GMES for a short time.<\/p>\n<p>\u201cThe user gets to control the intensity of the electrical impulse,\u201d Embrey says, \u201cand the system doesn\u2019t just run constantly. It automatically turns itself on or off depending on whether a person is moving\u201d<\/p>\n<h2>Putting it to the test<\/h2>\n<p>Embrey and his collaborators studied the use of the GMES in three groups of people. One of those groups included <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20434604\/\" target=\"_blank\" rel=\"noopener\">stroke survivors experiencing hemiplegia<\/a>, paralysis on one side of the body. One of the most common side effects of a stroke, hemiplegia can make it difficult for a person to walk and maintain balance.<\/p>\n<p>The other two studies focused on <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03226860\" target=\"_blank\" rel=\"noopener\">children with cerebral palsy<\/a> and <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28595744\/\" target=\"_blank\" rel=\"noopener\">adults with peripheral artery disease<\/a>, a condition that can cause debilitating cramping in the legs.<\/p>\n<p>Participants in all three studies wore the GMES for six to eight hours a day over the course of eight to 12 weeks, and the results were impressive: The GMES improved walking speed, walking endurance, muscle strength, quality of life and ability to function for all groups.<\/p>\n<p>\u201cThere was one study participant in his 40s who had suffered a stroke and could barely walk,\u201d says Embrey. \u201cThe GMES improved his walking ability to the point he could drive again and even return to work. It made a dramatic difference in his life.\u201d<\/p>\n<p>Something else that makes the GMES unique? Studies show that is has carryover effects. This means that for eight to 12 weeks after participants stopped wearing the GMES, the improvements to their walking ability remained.<\/p>\n<p>\u201cWe think the reason is the length of time patients were wearing the device each day,\u201d Embrey says. \u201cEvery single step they took in that 6-to-8-hour window was timed properly, supporting the brain\u2019s ability to re-learn how to coordinate walking.\u201d<\/p>\n<p>Throughout the research and development process, support from the <a href=\"https:\/\/updates-www.mccdn.io\/services\/research\/\">MultiCare Institute for Research &amp; Innovation (MIRI<\/a>) proved essential to Embrey and his team.<\/p>\n<p>\u201cDavid\u2019s project is the perfect example of how we help MultiCare employees translate their creativity into innovations that positively impact patient care,\u201d says Anne Reedy, vice president of research at MultiCare. \u201cWith support in areas such as research protocol design, grant applications, data collection and analysis and the dissemination of findings, they can research what they care about and play a role in improving health care for those in the community and beyond.\u201d<\/p>\n<h2>Overcoming the market hurdle<\/h2>\n<p>Over the course of 18 years, Embrey and his team conducted multiple research studies showing the GMES was safe, comfortable and effective. They received two patents, developed multiple prototypes and earned two President\u2019s Awards from MultiCare. However, one big hurdle remained: commercializing it so it could be available for patients at an affordable price.<\/p>\n<p>\u201cGetting a product like this to market requires time, expertise and funding I just didn\u2019t have \u2014 investment in the millions, marketing prowess, legal and regulatory knowledge, and so much more,\u201d says Embrey.<\/p>\n<p>By 2021, development of the GMES had stalled and Embrey was ready to retire. It seemed the project would go nowhere.<\/p>\n<p>But once again, disappointment and frustration gave way to hope. This time via telephone call. The <a href=\"https:\/\/ii4change.com\/innovation-lab\/\" target=\"_blank\" rel=\"noopener\">Innovation Institute<\/a>, an organization that works with health care professionals and communities to evaluate ideas and bring them to market, called Embrey. Already in partnership with MultiCare, the Innovation Institute saw value in the GMES and wanted to help Embrey realize his dream.<\/p>\n<p>Now Embrey, MultiCare and the team at the Innovation Institute are close to releasing a new prototype, and they are working toward completing the necessary steps to receive clearance from the <a href=\"https:\/\/www.fda.gov\/\" target=\"_blank\" rel=\"noopener\">U.S. Food and Drug Administration<\/a>, a requirement for all medical devices.<\/p>\n<p>\u201cThis hasn\u2019t been an experience marked by instant gratification, but I\u2019ve appreciated being able to celebrate small successes along the way,\u201d Embrey says. \u201cPlus, it\u2019s really exciting to be at this stage with the Innovation Institute and actively working toward getting the GMES to patients.\u201d<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Once every second \u2014 on average that\u2019s how often we take a step while walking. Many of us are concerned with the accumulation of those steps \u2014 striving for 10,000 a day, perhaps \u2014 rather than the mechanics of each one, but not David Embrey, PT, PhD. Embrey, a retired pediatric physical therapist at MultiCare [&hellip;]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":367,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[103],"tags":[],"class_list":["post-19795","post","type-post","status-publish","format-standard","hentry","category-research"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Enhancing stroke survivor&#039;s lives - MultiCare Vitals<\/title>\n<meta name=\"description\" content=\"The Gait MyoElectric Stimulator (GMES) medical device was designed to help people with conditions that affect their ability to walk.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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