{"id":35121,"date":"2024-09-30T07:00:49","date_gmt":"2024-09-30T07:00:49","guid":{"rendered":"https:\/\/updates-www.mccdn.io\/vitals\/?p=35121"},"modified":"2025-11-19T23:36:43","modified_gmt":"2025-11-19T23:36:43","slug":"what-have-we-learned-about-covid-19","status":"publish","type":"post","link":"https:\/\/updates-www.mccdn.io\/vitals\/what-have-we-learned-about-covid-19\/","title":{"rendered":"What have we learned about COVID-19?","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p>When the virus that causes COVID-19 sparked a global pandemic in 2020, questions about this pathogen far exceeded answers. How does it spread? Can we get it from contaminated objects or surfaces? Why do some people get really sick when others don\u2019t?<\/p>\n<p>While some mysteries remain, there is also a lot we have learned about COVID-19 since it upended our lives four years ago \u2014 from how it transmits to how long immunity is likely to last. In this <a href=\"https:\/\/updates-www.mccdn.io\/vitals\/what-have-we-learned-about-long-covid\/\">two-part series<\/a>, find out what we know now about COVID-19.<\/p>\n<h2><strong>Why COVID-19 affects people differently<\/strong><\/h2>\n<p>Some people with a COVID infection experience cold-like symptoms that last a few days, while others may be ill for weeks or even require hospitalization. There are many factors that influence how sick a person gets.<\/p>\n<p>People 50 and older or those with an underlying medical condition, like diabetes or heart disease, are at higher risk of experiencing severe illness. This is because their immune systems may have more difficulty fighting the virus.<\/p>\n<p>How sick you get also depends on your viral load \u2014 the amount of virus particles in your body. If the viral load is minimal, your immune system may be able to clear the virus quickly and you may experience few or no symptoms. If your viral load is high, you\u2019re more likely to experience severe symptoms for longer.<\/p>\n<p>Perhaps the biggest factor shaping our experience with COVID-19 that we have control over is vaccination status.<\/p>\n<p>\u201cSeveral studies have now shown how effective the vaccines are at reducing the severity of infections and preventing both hospitalizations and deaths,\u201d says <a href=\"https:\/\/updates-www.mccdn.io\/provider\/mary-p-fairchok\/\">Mary Fairchok, MD, a pediatric infectious disease specialist<\/a> at <a href=\"https:\/\/www.marybridge.org\/services\/infectious-disease\/\">MultiCare Mary Bridge Children\u2019s Hospital<\/a>.<\/p>\n<p><a href=\"https:\/\/www.thelancet.com\/journals\/lanres\/article\/PIIS2213-2600(24)00179-6\/fulltext\">A study published in The Lancet<\/a> that collected COVID-19 data in Europe through March 2023 found that the vaccines saved 1.6 million lives and reduced deaths by 59 percent.<\/p>\n<h2><strong>How some people seem to avoid infection<\/strong><\/h2>\n<p>Most of us by now have had a COVID-19 infection at least once, but there are people, sometimes referred to as \u201csuperdodgers,\u201d who have never tested positive or developed symptoms. This is likely, in part, due to individual habits and behaviors.<\/p>\n<p>\u201cIf you managed to avoid COVID early on in the pandemic and got vaccinated, then there\u2019s a high chance that at some point after vaccination, you may have actually gotten infected, but it was so mild you didn\u2019t notice or test positive,\u201d Dr. Fairchok says.<\/p>\n<p>Biology and genetics may play a role, too. <a href=\"https:\/\/www.nature.com\/articles\/s41586-024-07575-x\">A study published in Nature<\/a> found that some people who were exposed to the virus experienced abortive infections, meaning they never developed symptoms or tested positive. There were two notable aspects about this group of study participants:<\/p>\n<ul>\n<li>They had a much faster immune response in their nasal tissue than others did, which prevented the virus from reaching the respiratory tract and other parts of the body.<\/li>\n<li>They had a specific gene that was expressed at a much higher level in their nasal cells, which likely helped these cells fight the infection.<\/li>\n<\/ul>\n<h2><strong>Why kids tend to have mild COVID-19 symptoms<\/strong><\/h2>\n<p>While some kids experience severe illness from COVID-19, most only develop mild symptoms or have a symptom-free infection. This has led some to wonder whether kids get infected at all.<\/p>\n<p>It turns out \u2014 they do. In fact, more than <a href=\"https:\/\/covid.cdc.gov\/covid-data-tracker\/#pediatric-seroprevalence\">90 percent of kids 4 and under in the United States have been infected<\/a>. So what seems to shield many children from severe disease?<\/p>\n<p>The secret may lie in their noses. Similar to findings in the Nature study around nasal cells, <a href=\"https:\/\/www.cell.com\/cell\/abstract\/S0092-8674(23)00978-9\">a study published in Cell<\/a> found that kids produced much higher amounts of two proteins in the nose than adults do \u2014 one protein stops viruses from replicating and the other protein recruits immune cells to fight off infections.<\/p>\n<p>\u201cThis indicates that kids may be better able to nip this particular virus in the bud in their noses, preventing it from traveling down the respiratory tract to other areas of the body,\u201d Dr. Fairchok explains.<\/p>\n<h2><strong>How the virus spreads<\/strong><\/h2>\n<p>In the early days of the pandemic, many of us were wiping down groceries and vigilantly sanitizing countertops. Since then, we have learned that you aren\u2019t likely to pick up an infection simply by touching a contaminated surface.<\/p>\n<p>The main way COVID-19 spreads is through aerosols \u2014 tiny droplets released when breathing and talking that can hang in the air for a long period of time and travel across distances. Larger droplets emitted by a sneeze or cough can also cause an infection. While standing six feet away from someone (a recommendation early on in the pandemic) may help protect you from inhaling larger droplets, it doesn\u2019t protect you from aerosols.<\/p>\n<p>\u201cThis is why ventilation in crowded spaces and the kind of mask worn became so important,\u201d Dr. Fairchok says. \u201cN95 and KN95 masks are the best at keeping these tiny airborne particles from getting into your lungs.\u201d<\/p>\n<h2><strong>How long immunity lasts<\/strong><\/h2>\n<p>Immunity varies from person to person, and it also depends on how quickly the virus mutates (changes).<\/p>\n<p>\u201cImmunity, whether from vaccination or a previous infection, tends to wane after about three months,\u201d Dr. Fairchok says. \u201cHowever, protection from severe illness lasts longer, about four to six months.\u201d<\/p>\n<p>A <a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2118691\">study in The New England Journal of Medicine<\/a> indicates that hybrid immunity \u2014 from both vaccination and prior infection \u2014 provides the best protection and in some cases can last for more than a year.<\/p>\n<h2><strong>How long you\u2019re contagious<\/strong><\/h2>\n<p>If you have COVID-19, or another contagious respiratory virus, the CDC recommends staying home and away from others until your symptoms are improving <strong>and<\/strong> you\u2019re fever-free \u2014 without medications \u2014 for 24 hours.* The CDC also recommends taking additional precautions, such as masking, for the next five days.<\/p>\n<p>Dr. Fairchok adds that this guidance doesn\u2019t mean you stop being contagious at that 24-hour mark.<\/p>\n<p>\u201cPeople can still be contagious and spread the virus for approximately 8-10 days after first experiencing symptoms. This is why the CDC recommends taking added precautions, such as wearing a mask, once you resume normal activities.\u201d<\/p>\n<p>In the next installment of this series, find out what we\u2019ve learned about long COVID, including <a href=\"https:\/\/updates-www.mccdn.io\/vitals\/what-have-we-learned-about-long-covid\/\">what MultiCare experts have learned<\/a> about long COVID.<\/p>\n<p><em>*COVID-19 infection guidance differs for those who work in health care settings. <\/em><a href=\"https:\/\/www.cdc.gov\/covid\/hcp\/infection-control\/guidance-risk-assesment-hcp.html\"><em>Visit the CDC website<\/em><\/a><em> to learn more.\u00a0<\/em><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>When the virus that causes COVID-19 sparked a global pandemic in 2020, questions about this pathogen far exceeded answers. How does it spread? Can we get it from contaminated objects or surfaces? Why do some people get really sick when others don\u2019t? While some mysteries remain, there is also a lot we have learned about [&hellip;]<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":367,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[51,127,67],"tags":[],"class_list":["post-35121","post","type-post","status-publish","format-standard","hentry","category-covid-19","category-healthy-living","category-kids-health"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.6 (Yoast SEO v27.6) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What we\u2019ve learned about COVID-19 infection and prevention - MultiCare Vitals<\/title>\n<meta name=\"description\" content=\"While some mysteries remain, there is also a lot we have learned about COVID-19 \u2014 from how it transmits to how long immunity is likely to last.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/updates-www.mccdn.io\/vitals\/what-have-we-learned-about-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What we\u2019ve learned about COVID-19 infection and prevention - 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